Considerations To Know About ceesdekker
Considerations To Know About ceesdekker
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Working with solitary-molecule optical and AFM imaging and force-spectroscopy procedures, we request to unravel the mechanistic areas of the construction and dynamics of chromosomes. Our study pursuits incorporate:
Human Rad51 filaments on double- and single-stranded DNA: correlating standard and irregular sorts with recombination operate.
Multicolor imaging of your bacterial nucleoid and mobile division proteins with blue, orange, and around-infrared fluorescent proteins
Because 2000, Dekker has shifted the principle focus of his perform to biophysics where he reports the Attributes of single biomolecules and cells using the instruments of nanotechnology. This alteration of area was driven by his fascination to the amazing functioning of biological molecular structures, and also because of the extensive-term viewpoint that lots of appealing discoveries is usually expected Within this area.[5] Recent strains of exploration in his biophysics team are during the parts of:[six]
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The coiled-coil of your human Rad50 DNA mend protein includes specific segments of greater versatility
Length control of individual carbon nanotubes by nanostructuring with the scanning tunneling microscope
Dynamic ParB–DNA interactions initiate and maintain a partition condensate for bacterial chromosome segregation
The rotors harness energy from the nanoscale drinking water and cees dekker ion flow that may be produced by a static chemical or electrochemical prospective gradient in the nanopore, which happen to be recognized through a salt gradient or used voltage, respectively. These artificial nanoengines self-Manage and function autonomously in physiological circumstances, suggesting solutions to setting up Electrical power-transducing motors at nanoscale interfaces.
It absolutely was during this period that Dekker carried out analysis on magnetic spin programs and on sound in superconductors and semiconductors.
‘The idea that There exists this type of detail as a beginning, an enormous bang, is by now a fascinating signpost to consider that there was a creator. But much more normally, and on The idea of pure rationality, I also get there in a Christian interpretation of fact. An atheistic worldview is usually a naturalistic worldview: essentially, there are only atoms and all-natural forces that we could evaluate.
1999, to start with measurement in the wavefunction of one molecular orbitals of carbon nanotubes; and discovery of kink heterojunctions of carbon nanotubes which gave decisive evidence for the new Luttinger description of interacting electrons in nanotubes
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It was an exceptionally interesting time, for the duration of which I been given lots of help from Delft College of Technologies, the place I had been a professor at the time, and I started out various collaborations with molecular biologists. That served me learn a whole lot.’